Important for doctors

Can patients’ imaging results be affected by a ketogenic diet?

The answer is yes when it comes to brain PET scans. Recently, researchers proved that patients on a ketogenic diet can have lower cerebral 18F-FDG uptake on PET imaging. This study, according to experts who participated in the analysis, adds to the growing body of evidence indicating that physicians should pay attention to patients’ dietary habits as the keto diet gains popularity. Important for doctors

According to corresponding author O. A. Bennett of Prince of Wales Hospital in Sydney, Australia, and co-authors, “Because of this range of proven and postulated benefits of ketosis, more patients are attending 2-[18F]fluoro-2-deoxy-D-glucose (18F-FDG) positron emission tomography (PET) of the brain while in therapeutic ketosis.” Understanding how ketosis affects these images is important because ketones can serve as a metabolic substrate for the brain. Important for doctors

Experts discovered a negative correlation between serum glucose levels and whole brain 18F-FDG uptake in 52 ketogenic diet patients who underwent PET scans of the brain. Standardized uptake values (SUVbw) based on body weight decreased when serum ketones levels increased, as they discovered.

Making sense of the meaning of these discoveries, that’s what the creators noticed “the 18F-FDG take-up related with ketones probably mirrors a genuine decrease in glucose digestion by the mind because of the special utilization of ketone bodies as another energy substrate free of glucose accessibility.” World News Spot


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